CURRICULUM VITAE
Keril j. blight

PubMed Publications: for blight + KJ
Division of Biology and Biomedical Sciences profile

Education:

1990	B.Sc. (Hons), University of Adelaide, Australia
1994	Ph.D., University of Adelaide, Australia

Academic Positions:

1995-2001	Postdoctoral Fellow, Washington University School of Medicine, St. Louis, Missouri
2001-2002	Research Assistant Professor, Center for the Study of Hepatitis C, The Rockefeller University, New York, New York
2002-present	Assistant Professor, Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO

Honors and Awards:

1992	Dawes Postgraduate Research Scholarship
1992	Japanese Society of Gastroenterology Travel Award
1994	Dora Lush (Biomedical) Postgraduate Research Scholarship, National Health and Medical Research Council of Australia
1999	American Association for the Study of Liver Diseases Junior Investigator Travel Award
2002	Wellcome Trust Overseas Senior Research Fellowship in Biomedical Science (declined)
2003-2007	The Ellison Medical Foundation New Scholar Award in Global Infectious Diseases
2006	American Cancer Society Award of Excellence

Editorial Service:

Editorial boards:
Virology (2006-present)
Journal of Virology (2007-present)

Adhoc reviewer:
Hepatology
Journal of General Virology
Journal of Infectious Diseases
Nucleic Acids Research
Virus Research

Publications:

Peer-Reviewed:

1. Blight K, Trowbridge R, Rowland R and Gowans E. Detection of hepatitis C virus RNA by in situ hybridization. Liver 1992; 12:286-289.
2. Blight K, Lesniewski R, LaBrooy J, Trowbridge R and Gowans E. Localisation of hepatitis C virus proteins in infected liver tissue by immunofluorescence. Gastroenterol. Jpn. 1993; 28:55-58.
3. Blight K, Rowland R, Hall PDM, Lesniewski RR, Trowbridge R, LaBrooy JT and Gowans EJ. Immunohistochemical detection of the NS4 antigen of hepatitis C virus and its relation to histopathology. Am. J. Pathol. 1993; 143:1568-1573.
4. Blight K, Lesniewski RR, LaBrooy JT and Gowans EJ. Detection and distribution of hepatitis C-specific antigens in naturally infected liver. Hepatology 1994; 20:553-557.
5. Blight K, Trowbridge R and Gowans EJ. Absence of double-stranded replicative forms of HCV RNA in liver tissue from chronically infected patients. J. Viral Hep. 1996; 3:29-36.
6. Deleersnyder V, Pillez A, Wychowski C, Blight K, Xu J, Hahn YS, Rice CM and Dubuisson J. Formation of native hepatitis C virus glycoprotein complexes. J. Virol. 1997; 71:697-704.
7. Blight KJ and Rice CM. Secondary structure determination of the conserved 98-base sequence at the 3' terminus of hepatitis C virus genome RNA. J. Virol. 1997; 71:7345-7352.
8. Kolykhalov AA, Agapov EV, Blight KJ, Mihalik K, Feinstone SM and Rice CM. Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA. Science 1997; 277:570-574.
9. Blight KJ, Kolykhalov AA and Rice CM. Efficient initiation of HCV RNA replication in cell culture. Science 2000; 290:1972-1975.
10. Buonocore L, Blight KJ, Rice CM and Rose JK. Characterization of vesicular stomatitis virus recombinants that express and incorporate high levels of hepatitis C virus glycoproteins. J. Virol. 2002; 76:6865-6872.
11. Blight KJ, McKeating JA and Rice CM. Highly permissive cell lines for subgenomic and genomic hepatitis C virus replication. J. Virol. 2002; 76:13001-13014.
12. Hardy R, Marcotrigiano J, Blight KJ, Majors JE and Rice CM. Hepatitis C virus RNA synthesis in a cell-free system isolated from replicon-containing hepatoma cells. J. Virol. 2003; 77:2029-2037.
13. Blight KJ, McKeating JA, Marcotrigiano J and Rice CM. Efficient replication of hepatitis C virus genotype 1a RNAs in cell culture. J. Virol. 2003; 77:3181-3190.
14. Blight KJ. Allelic variation in the hepatitis C virus NS4B protein dramatically influences RNA replication. J. Virol. 2007; 81:5724-5736.
15. Paredes AM and Blight KJ. A genetic interaction between hepatitis C virus NS4B and NS3 is important for RNA replication. J. Virol. 2008; 82:10671-10683.

1. Gowans EJ, Blight K, Arthur J and Higgins GD. Detection of virus nucleic acids by radioactive and nonisotopic in situ hybridization. Methods Mol. Biol. 1994; 33:243-256.
2. Gowans EJ, Arthur J, Blight K and Higgins GD. Application of in situ hybridization for the detection of virus nucleic acids. Methods Mol. Biol. 1994; 33:395-408.
3. Blight KJ and Gowans EJ. In situ hybridization and immunohistochemical staining for hepatitis C virus products. Viral Hepatitis Reviews 1995; 1:143-155.
4. Rice CM, Kolykhalov AA, Lin C, Reed K, Agapov E, Blight K, Xu J and Grakoui A. Hepatitis C virus genome organization and expression: potential antiviral targets. Antiviral Therapy 1996; 1:11-17.
5. Blight KJ, Kolykhalov AA, Reed KE, Agapov EV and Rice CM. Molecular virology of hepatitis C: an update with respect to potential antiviral targets. In: Therapies for Viral Hepatitis. R.F. Schinazi, J-P. Sommadossi and H.C. Thomas, eds. International Medical Press, London. 1998, pp. 207-217.
6. Blight KJ, Kolykhalov AA, Reed KE, Agapov EV and Rice CM. Molecular virology of hepatitis C: an update with respect to potential antiviral targets. Antiviral Therapy 1998; 3:71-81.
7. Blight KJ and Rice CM. Hepatitis C virus. In: Wiley Encyclopedia of Molecular Medicine. John Wiley & Sons, Inc. 2002, pp. 1599-1604.
8. Blight KJ, Grakoui A, Hanson H and Rice CM. The Molecular Biology of hepatitis C virus. In: Hepatitis Viruses. Ou J-H. J, ed. Kluwer Academic Publishers, Boston. 2002, pp. 81-108.
9. Blight KJ and Norgard EA. HCV replicon systems. In: Hepatitis C viruses: genomes and molecular biology. Tan, S-L. ed. Horizon Scientific Press, Norwich, UK. 2006, pp 311-351.
10. Blight KJ and Norgard EA. Recent advances in hepatitis C virus replication. In: Recent advances in RNA virus replication. Hefferon, K.L. ed. Transworld Reseach Network, Kerala, India. 2006, pp 45-90.