CURRICULUM VITAE
Daniel E. Goldberg

PubMed Publications: for goldberg + DE
Division of Biology and Biomedical Sciences profile

Education:

1979 - 1985	M.D. and Ph.D., Molecular Biology (Dr. Stuart Kornfeld), Washington University, St. Louis, MO
1978 - 1979	Research Assistant, Department of Biological Chemistry, laboratory of Dr. Eugene Kennedy, Harvard Medical School, Boston, MA
1975 - 1978	A.B., Harvard College, Cambridge, MA

Current Position:

Professor of Medicine and Co-chief, Division of Infectious Diseases
Professor of Molecular Microbiology,
Washington University School of Medicine, St. Louis, MO
Investigator, Howard Hughes Medical Institute

Academic Positions and Employment:

1995-97	Associate Professor, Washington University School of Medicine Assistant Investigator, Howard Hughes Medical Institute
1990 - 1994	Assistant Professor, Washington University School of Medicine
1988 - 1990	Research Associate, Laboratory of Medical Biochemistry (Dr. Anthony Cerami), Rockefeller University, New York, NY
1987 - 1988	Fellow in Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO
1985 - 1987	Resident in Internal Medicine, Brigham and Women's Hospital, Boston, MA

Bibliography:

Selected Publications, Last 5 years:

1. *Liu J, Istvan ES, Gluzman IY, Gross J, Goldberg DE: Plasmodium falciparum ensures its amino acid supply with multiple acquisition pathways and redundant proteolytic enzyme systems; Proc Natl Acad Sci USA 2006, 103: 8840-8845.
2. *Liu J, Istvan ES, Goldberg DE: Hemoglobin-degrading plasmepsin II is active as a monomer; J Biol Chem 2006, 281: 38682-38688.
3. *Ponpuak M, Klemba M, Gluzman IY, Goldberg DE: A role for falcilysin in transit peptide degradation in the Plasmodium falciparum apicoplast; Mol Micro 2007, 62: 314-334.
4. *Armstrong CA, Goldberg DE: An FKBP destabilization domain modulates protein levels in Plasmodium falciparum; Nature Methods 2007, 4: 1007-9.
5. *Drew M, Banerjee R, Uffman EW, Gilbertson S, Rosenthal PJ, Goldberg DE: Plasmodium food vacuole plasmepsins are activated by falcipains; J Biol Chem 2008, 283: 12870-76.
6. *Russo I, Oksman A, Vaupel B, Goldberg DE: A calpain unique to alveolates is essential in P. falciparum and its knockdown reveals an involvement in pre-S-phase development; Proc Natl Acad Sci USA 2009, 106: 1554-9.
7. *Russo I, Oksman A, Goldberg DE: Fatty acid acylation regulates trafficking of the unusual P. falciparum calpain to the nucleolus; Mol Micro 2009, 72: 229-245.
8. *Russo I, Babbitt S, Muralidharan V, Butler T, Oksman A, Goldberg DE: Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyte; Nature 2010, 463: 632-636.
9. *Istvan ES, Dharia NV, Gluzman I, Winzeler EA, Goldberg DE: Validation of isoleucine utilization targets in Plasmodium falciparum; Proc Natl Acad Sci USA 2011, in press.
10. *Muralidharan V, Oksman A, Iwamoto M, Wandless TJ, Goldberg DE: Asparagine repeat function in a Plasmodium falciparum protein assessed with a regulatable fluorescence affinity tag; Proc Natl Acad Sci USA 2011, in press.

Lab Members:

Research Assistant Professor
Eva Istvan                        PhD UT Southwestern

Post-doctoral Fellows
Vasant Muralidharan PhD         Rockefeller
May Paing PhD                           UNC
Jeremy Mallari PhD                   UCSF
Paul Sigala PhD                         Stanford

Students
Ericka Ricaldez            PhD
Shalon Babbitt             PhD
Tamira Butler               PhD
Priay Pal                        PhD
Kevin Kim                      BA
Samantha Hsieh         BA

Technicians
Anna Oksman              MS
Barb Vaupel                 MS
Rusiko Turabelidze    MD

Administrative Assistant
Mary Pichler