Washington University School of Medicine
Department of Molecular Microbiology
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CURRICULUM VITAE
David E. Kennell


PubMed Publications: for kennell + DE

Office Address: Department of Molecular Microbiology
Washington University School of Medicine
McDonnell Pediatric Research Building
Campus Box 8230
660 S. Euclid Ave.
St. Louis, MO 63110
   

 

 

Education:

1954 B.A. Physics, University of California, Berkeley, California
1959 Ph.D. Biophysics, University of California, Berkeley, California

Current Position:

Professor Emeritus Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri

Professional Experience and Appointments:

1969-1973 Associate Professor
Department of Microbiology, Washington University School of Medicine, St. Louis, Missouri
1963-1969 Assistant Professor
Department of Microbiology, Washington University School of Medicine, St. Louis, Missouri
1969-1974 Research Career Development Award, N.I.H.
1961-1963 Instructor
Department of Microbiology, Washington University School of Medicine, St. Louis, Missouri
1960-1961 Research Associate
Massachusetts Institute of Technology, Cambridge, Massachusetts
1959-1960 Research Fellow
Harvard University, Cambridge, Massachusetts
1959-1961 Postdoctoral Fellow
Public Health Service, National Cancer Institute
1957-1959 Predoctoral Fellow
Public Health Service, National Cancer Institute
1956-1957 Graduate Research Engineer 1 (Calorimetrist)
University of California, Berkeley, California

Editorial Responsibilites:

1986-1991 Editorial Board, Journal of Bacteriology
1972-1983 Editorial Board, Journal of Bacteriology

Peer Review Panels:

1981-1984 Member, NIH Microbial Physiology & Genetics Study Section II
1989-Present Member, NIH Reviewers Reserve (NRR)

Publications:

  1. Cannistraro, V.J. and Kennell, D. (1997). RNase YI* and RNA structure studies. Nucleic Acids Research 25: 1405-1411.
  2. Cannistraro, V.J. and Kennell, D. (1995). Identifying ends of infrequent RNA molecules in bacteria. In Methods in Molecular Genetics vol. 6 (ed. K.W. Adolph). Academic Press, Orlando, FL. pp 280-300.
  3. Cannistraro, V.J. and Kennell, D. (1994). The processive reaction mechanism of ribonuclease II. J. Mol. Biol. 243: 930-943.
  4. Lim, L.W., Mathur, S., Cannistraro, V.J. and Kennell, D. (1993). Preliminary X-ray crystallographic studies of ribonuclease I from Escherichia coli.. J. Mol. Biol. 234: 499-501.
  5. Mathur, S., Cannistraro, V.J. and Kennell, D. (1993). Identification of an intracellular pyrimidine-specific endoribonuclease in Bacillus subtilis. J. Bacteriol. 175: 6717-6720.
  6. Cannistraro, V.J. and Kennell, D. (1993). The 5'ends of RNA oligonucleotides in Escherichia coli and mRNA degradation. Europ. J. Biochem. 213: 285-293.
  7. Srivastava, S.K., Cannistraro, V.J. and Kennell, D. (1992). Broad-specificity endoribonucleases and mRNA degradation in Escherichia coli. J. Bacteriol. 174: 56-62.
  8. Cannistraro, V.J. and Kennell, D. (1991). RNase I*, a form of RNase I, and mRNA degradation in Escherichia coli. J. Bacteriol. 173:4653-4659.
  9. Meador, J. III and Kennell, D. (1990). Cloning and sequencing the gene encoding Escherichia coli ribonuclease I: exact physical mapping using the genome library. Gene 95:1-7.
  10. Meador, J. III, Cannon, B., Cannistraro, V.J. and Kennell, D. (1990). Purification and characterization of E. coli RNase I: comparisons with RNase M. Europ. J. Biochem. 187:549-553.
  11. Cannistraro, V.J. and Kennell, D. (1989). Purification and characterization of ribonuclease M and mRNA degradation in E. coli. Europ. J. Biochem. 181: 363-370.
  12. Subbarao, M.N. and Kennell, D. (1988). Evidence for endonucleolytic cleavages in decay of lacZ and lacI messenger RNAs. J. Bacteriol. 170: 2860-2865.
  13. Cannistraro, V.J., Hwang, P. and Kennell, D.E. (1987). Isolating and sequencing the predominant 3'-ends of a specific mRNA. J. Biochem. Biophys. Methods 14: 211-221.
  14. Cannistraro, V.J., Subbarao, M.N. and Kennell, D.E. (1986). Specific endonucleolytic cleavage sites for decay of E. coli mRNA. J. Mol. Biol. 192: 257-274.
  15. Kennell, D.E. (1986). The instability of messenger RNA in bacteria. In Maximizing Gene Expression (eds. W.S. Reznikoff and L. Gold) Butterworth Publ., Stoneham, MA., 101-140.
  16. Cannistraro, V.J. and Kennell, D. (1985). Evidence that the 5'-end of lac mRNA starts to decay as soon as it is synthesized. J. Bacteriol. 161: 820-822.
  17. Cannistraro, V.J. and Kennell, D.E. (1985). The 5'-ends of Escherichia coli lac mRNA. J. Mol. Biol. 182: 241-248.
  18. Cannistraro, V.J., Wice, B.M. and Kennell, D.E. (1985). Isolating and sequencing the predominant 5'-ends of a specific mRNA in cells. II. End-labeling and sequencing. J. Biochem. Biophys. Methods 11: 163-175.
  19. Cannistraro, V.J., Strominger, M.B., Wice, B.M. and Kennell, D.E. (1985). Isolating and sequencing the predominant 5'-ends of a specific mRNA in cells. I. Purification by filter hybridization. J. Biochem. Biophys. Methods 11: 153-161.

Technology for Licensing:


E.coli strain DK523. overproducing for RNase I.

 

 

 
 

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