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CURRICULUM VITAE
Jennifer K. Lodge
PubMed Publications: for lodge + JK
| Office Address: |
Department of Molecular Microbiology
Washington University School of Medicine
8250 McDonnell Pediatric Research Building
Campus Box 8230
660 S. Euclid Ave.
St. Louis, MO 63110
Phone, office: 314-286-2125
Email: lodgejk [at] wustl.edu |
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Education:
| 1979 |
B.A. with Honors, Oberlin College, Oberlin, OH |
| 1988 |
Ph.D., Washington University, St. Louis, MO |
Honors and Awards:
| 1982-1985 |
G-POP Predoctoral Fellowship |
| 1998-2001 |
Burroughs Wellcome New Investigator in Molecular Pathogenic Mycology |
| 2010 |
Fellow, American Academy of Microbiology |
| 2011 |
Fellow, AAAS |
Academic Positions:
| 2009 - present |
Professor, Department of Molecular Microbiology,
Washington University School of Medicine, St. Louis MO |
| 2009 - present |
Associate Dean for Research
Washington University School of Medicine, St. Louis MO |
| 2009-2011 |
Adjunct Professor, Department of Biochemistry and Molecular Biology,
Saint Louis University School of Medicine, St. Louis MO |
| 2007-2009 |
Professor, Department of Biochemistry and Molecular Biology
Saint Louis University School of Medicine, St. Louis MO |
| 2005-2007 |
Associate Dean for Research
Saint Louis University School of Medicine, St. Louis MO |
| 2003-2007 |
Associate Professor, Department of Biochemistry and Molecular Biology,
Saint Louis University School of Medicine, St. Louis MO |
| 2002-2009 |
Secondary Appointment, Department of Molecular Microbiology and Immunology
Saint Louis University School of Medicine, St. Louis MO |
| 1998-2003 |
Assistant Professor, Department of Biochemistry and Molecular Biology,
Saint Louis University School of Medicine, St. Louis MO |
| 1995-1997 |
Research Assistant Professor, Dept. of Molecular Biology and Pharmacology
Washington University School of Medicine, St. Louis MO |
| 1993-1995 |
Research Instructor, Department of Molecular Biology and Pharmacology,
Washington University School of Medicine, St. Louis MO |
Patents:
Kaniewski, W., J. K. Lodge and N. E. Tumer. Virus resistant potato plants (1992) Patent 6,015,940 38-21(10547)A
Selected Publications:
- Lam, WC, Gerik, KJ, and Lodge, JK (2012) Role of Cryptococcus neoformans Rho1 GTPases in the PKC1 signaling pathway in response to thermal stress. Eukaryotic Cell. Accepted with minor revision.
- Gilbert NM, Baker LG, Specht, CA and Lodge JK. (2012) A glycosylphosphatidylinositol anchor is required for membrane localization but dispensable for cell wall association of chitin deacetylase 2 in Cryptococcus neoformans. mBio In press.
- Baker LG, Specht CA and Lodge JK. (2011) Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans. Eukaryot Cell. 10:1264-8.
- Brown, S.M., Upadhya, R. Shoemaker, J.D., and Lodge, J.K. (2010) Isocitrate Dehydrogenase is Important for Nitrosative Stress Resistance in Cryptococcus nerformans, but Oxidative Stress Resistance in Not Dependant on Glucose-6-Phosphate Dehydrogenase. Eukaryotic Cell. 2010 Jun;9(6):971-80. PMID 20400467.
- Gilbert NM, Donlin MJ, Gerik KJ, Specht CA, Djordjevic JT, Wilson CF, Sorrell TC, Lodge JK. (2010) KRE genes are required for beta-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans. Mol. Microb. 76(2):517-34. PMID 20384682.
- Baker LG, Specht CA, and Lodge JK. (2009) Chitinases are essential for sexual development but not vegetative growth in Cryptococcus neoformans. Eukaryotic Cell. 8:1692-705. Epub 2009 Sep. 4. PMID 19734369.
- Gerik, K.J, Bhimireddy, S. R., Ryerse J. S., Specht, C. A. and Lodge, J.K. (2008) Protein Kinase C1 (PKC1) is essential for protection against both oxidative and nitrosative stress, cell integrity, and normal manifestation of virulence factors in the pathogenic fungus Cryptococcus neoformans. Eukaryotic Cell, 7:1685-98. PMID 18689526.
- Brown, S.M., Campbell, L. T. and Lodge, J.K. (2007) Cryptococcus neoformans: A Fungus Under Stress. Current Opinions in Microbiology. 10:320-5. PMID 177076585.
- Baker L.G., Specht, C. A. Donlin, M. J. and Lodge, J. K. (2007) Chitosan, the deacetylated form of chitin, is necessary for cell wall integrity in Cryptococcus neoformans. Eukaryotic Cell. 6:855-867. PMID 17400891.
- Missall T.A, Pusateri M.E., Donlin M.J., Chambers K.T., Corbett J.A., and Lodge J.K. (2006) Post-translational, translational, and transcriptional responses to nitric oxide stress in Cryptococcus neoformans: implications for virulence. Eukaryotic Cell. 5:518-529. PMID 16524907.
- Banks, I. R., Specht, C. A., Donlin M.J., Gerik K. J., and Lodge J.,K. (2005) Chitin and Chitosan are critical for growth in the fungal pathogen Cryptococcus neoformans. Eukaryotic Cell, 4:1902-12. PMID 16278457
- Missall, T.A. and Lodge, J.K. (2005) Function of the thioredoxin proteins in Cryptococcus neoformans during stress or virulence and regulation by putative transcriptional modulators. Molecular Microbiology, 57:847-858. PMID 16045626
- Missall, T.A., Cherry-Harris, J.F. and Lodge, J.K. (2005) Two glutathione peroxidases in the fungal pathogen, Cryptococcus neoformans, are expressed in the presence of specific substrates. Microbiology 151: 2573-2581. PMID 16079336
- Gerik, K.J., Donlin, M.J., Soto C.E., Banks, A.M., Banks I.R., Maligie, M.A., Selitrennikoff, C.P. and Lodge, J.K. (2005) Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans. 58: 393-408. PMID 16194228.
- Loftus,B, Eula Fung E, Roncaglia P, Rowley D, Amedeo P, Bruno D, Vamathevan J, Miranda M, Anderson I, Fraser JA, Allen J, Bosdet I, Brent MR, Chiu R, Doering TL, Donlin MJ, D’Souza CL, Fox DS, Grinberg V, Fu J, Fukushima M, Haas B, Huang JC, Janbon G, Jones,S, Krzywinski MI, Kwon-Chung J, Lengeler KB, Maiti R, Marra M, Marra RE, Mathewson C, Mitchell TG, Pertea M, Riggs F, Salzberg SL, Schein J, Shvartsbeyn A, Shin,H, Specht C, Suh B, Tenney A, Utterback T, Wickes BL, Wye N, Kronstad JW, Lodge JK, Heitman J, Davis RW, Fraser CM, and Hyman RW. (2005) The genome and transcriptome of Cryptococcus neoformans, a basidiomycetous fungal pathogen of humans Science 307:1321-1324. PMID 15653466
- Missall, T. A., Moran, J. M., Corbett, J. A., and Lodge, J. K. (2005) Distinct stress responses of two functional laccases in Cryptococcus neoformans is revealed in the absence of the thiol-specific antioxidant, Tsa1. Eukaryotic Cell. 4:202-8. PMID 15643075
- Missall T. A. and Lodge, J.K. (2005) Thioredoxin reductase is essential for viability in the fungal pathogen, Cryptococcus neoformans Eukaryotic Cell 4:487-9. PMID 15701811
- Missall, T. A, Pusateri, M. E. and Lodge, J. K. (2004) Thiol peroxidase is critical for virulence and resistance to nitric oxide and peroxide in the fungal pathogen, Cryptococcus neoformans. Mol. Microbiology 51:1447-1458. PMID 14982637.
- Nelson, R.T., Pryor, B., and Lodge, J.K. (2003) Sequence length required for homologous recombination in Cryptococcus neoformans. Fungal Genetics and Biology 38:1-9. PMID 12553931.
- Nelson, R.T., Hua, J., Pryor, B., and Lodge, J.K. (2001) Identification of virulence mutants of the fungal pathogen, Cryptococcus neoformans using signature tagged mutagenesis. Genetics 157:935-947. PMID 11238384.
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