Curriculum Vitae
Joseph P. Vogel


PubMed Publications: for vogel + JP
Division of Biology and Biomedical Sciences profile

Office Address:

Department of Molecular Microbiology
Washington University School of Medicine
660 S. Euclid Ave.
St. Louis, MO 63110
Phone, office: 314-747-1029
Phone, lab: 314-747-1030
FAX: 314-362-1232
Email: jvogel [at] wustl.edu

   

 

 

Education:

1993 Ph.D., Molecular Biology Princeton University, NJ
1986 B.S, Biology Minnesota State University, MN
          B.S, Chemistry Minnesota State University, MN
          B.S, Biochemistry Minnesota State University, MN

Academic Positions:

2007-present Associate Professor, Department of Molecular Microbiology Washington University School of Medicine, St. Louis, MO

1998-2007 Assistant Professor, Department of Molecular Microbiology Washington University School of Medicine, St. Louis, MO

1993-1998
Postdoctoral Research Fellow (Isberg laboratory), Department of Molecular Biology and Microbiology Tufts University                     School of Medicine, Boston, MA

Honors and Awards:

1999-2001 Whitaker Young Investigator Award

1996-1998 Medical Foundation Award

1994-1996 Howard Hughes Associate

1991-1992 Bristol-Myers Squibb Fellowship

Departmental Service:

Previous:
Organized the Infectious Diseases/Basic Microbiological Mechanisms Research Conference (1999, 2000, 2001, 2002, 2003).
Organized the Molecular Microbiology and Microbial Pathogenesis Program Retreat (1999, 2000, 2001, 2002).
Served on the Department of Molecular Microbiology faculty search committee that hired Dr. Niraj Tolia (2007).

Current:
Department of Molecular Microbiology Postdoctoral & Predoctoral grants committee (2006 & 2007).
Department of Molecular Microbiology web design committee.

University Service:

Previous:
Served on the Graduate Admissions Committee B (Molecular Microbiology and Microbial Pathogenesis Program) (2000, 2001, 2002, 2003, 2004, 2005, 2006, 2007).
Served on the Washington University Distinguished Investigator Award committee (2007).
Attended the 2007 Annual Biomedical Research Conference for Minority Students (ABRCMS) in Austin, TX.
Assistant Program Director for the Molecular Microbiology and Microbial Pathogenesis Program (2007).
Course Master for the Molecular Microbiology and Microbial Pathogenesis Journal Club (Biol 5416) (2001-2007).
Course Master for the Infectious Diseases/Basic Microbiological Mechanisms Research Conference (2002-2005).

Current:
Co-Course Master for the Molecular Microbiology and Microbial Pathogenesis Graduate Course (Biol 5392) (2009). *will take over the course in 2010.
Molecular Microbiology and Microbial Pathogenesis Program Steering Committee (2000-2008).
Department of Molecular Microbiology representative to the Faculty of Arts and Sciences (2006-2008).

Thesis committees:
Juan Martinez (Hultgren)
Melisa Lim (Kunkel)
Neil Suranan (St. Geme)
Nat Moorman (Speck)
Travis Jewett (Sibley)
Michael Meehl (Caparon)
Damon Ellison (Miller)
Brad Weart (Levin)
Chris Marion (Goldman)
Charles Rexer (Chalker)
Luke Starnes (Sibley)
Thomas Kelh Fie (St. Geme)
Scott Handely (Miller)
Colin Kietzman (Caparon)
Sarah Witowski (Miller)
N’Goundo Magassa
(Caparon) Mike Mandell
(Beverley) Zach Cusumano
(Caparon) Sarah Fentress (Sibley)
Bisco Hill (Levin)
Suki Chandrasekaran (Caparon)

Qualifying exams:
Jennie Lovett
Doran Fink
Maureen Jones
Jeff Long McGee
Amy Zoch
Steve De Lira
Matt Lawlor
Gregory Anderson
Dawn Wentzel
Lloyd Robinson
Chris Marion
Erin Brosnahan
Brad Weart
Jason Cathelyn
Amy Lee
Jason Rosch
Aki Yoneda
Morgann Reilly
Jennifer Loughman
Simren Mehta
Tracey Nicholson
David Rosen
Ann Gaynor
Jose Haslam

Teaching
Lecturer in Special Topics in Microbial Pathogenesis (Biol 5217) – one lecture/year (1999-2008).
Lecturer in Medical Microbes & Pathogenesis (M 30 526) – one and one half lectures/year for 1999-2005 and two and one half lectures for 2006-2008.
Lecturer in Molecular Microbiology and Microbial Pathogenesis (Biol 5392) – three lectures/year (1999-2008).

National/World Service:

Editorial board
Infection & Immunity (2006-2008)
Molecular Microbiology (2007-2008)

Reviewer for the following journals:
Applied Environmental Microbiology
Cellular Microbiology
Environmantal Microbiology
Infection & Immunity
Journal of Bacteriology
Journal of Biochemistry
Journal of Experimental Medicine
Molecular Microbiology
Nature
Nature Genetics
Nature Medicine
PLOS Genetics
PLOS Pathogen
Science
Trends in Microbiology
           
Grant reviewer:
Ad hoc reviewer for NIH study section.
Ad hoc reviewer for the MRC.

Meeting organizer:
ASM General Meeting (2006).  Co-convener of session titled:
“Cytoskeleton and Cellular Organization in Bacteria”
17th Annual Midwest Microbial Pathogenesis Conference (2010).

Publications - Reviews/Books chapters:

1. LeBlanc JJ and Vogel JP. 2008. The Dot/Icm type IVB secretion system. In Legionella pneumophila: Pathogenesis and Immunity. Eds. P. Hoffman, H. Friedman, and M. Bendinelli. Springer, New York, NY. Pages 49-64.

2. Vincent CD and Vogel JP. 2008. The Dot/Icm type IVB secretion system of Legionella. In Legionella: Molecular Biology. Eds K. Heuner and M. Swanson. Caister Academic Press, Norfolk, UK. Pages 165-180.

3. Vincent CD, Jeong KC, Sexton J, Buford E, Vogel JP. 2006. The Legionella pneumophila Dot/Icm Type IV Secretion System. In Legionella: State of the Art 30 Years After Its Recognition. Ed. N. Cianciotto et al, ASM Press, Washington, D.C. Pages 184-191.

4. Jeong KC, Vincent C, Buford E, Vogel JP. 2006. Subcellular localization of the Dot/Icm type IV secretion proteins. In Legionella: State of the Art 30 Years After Its Recognition. Ed. N. Cianciotto et al, ASM Press, Washington, D.C. Pages 192-194.

5. Vincent C, Friedman J, Vogel JP. 2006. Defining the translocation pathway of the Legionella pneumophila type IV secretion system. In Legionella: State of the Art 30 Years After Its Recognition. Ed. N. Cianciotto et al, ASM Press, Washington, D.C. Pages 195-198.

6. Buchrieser C, Hoffman P, Russo J, Vogel JP. 2006. Genome Sequencing and Genomics. In Legionella: State of the Art 30 Years After Its Recognition. Ed. N. Cianciotto et al, ASM Press, Washington, D.C. Pages 377-380.

7. Vogel JP. 2004. Turning a tiger into a house cat: using Legionella pneumophila to study Coxiella burnetii. Trends in Micro. 8:354-60.

8. Sexton JA, Vogel JP. 2002. Type IVB secretion by intracellular pathogens. Traffic 3:178-85.

9. Christie, PJ, Vogel JP. 2000. Bacterial type IV secretion: conjugation systems adapted to deliver effector molecules to host cells. Trends Micro. 8:354-60.

10. Vogel JP, Isberg RR. 1999. Cell biology of Legionella pneumophila. Current Opinions in Microbiology. 2:30-34.

11. Rose MD, Vogel JP. 1994. KAR2. A Guidebook to the secretory pathway, Rothblatt, J.A. et al., eds., Oxford University Press.

Publications - Peer reviewed papers:

    1. Vincent CD, Jeong KC, Friedman JR, Vogel JP. 2006. Identification of the core transmembrane complex of the Legionella Dot/Icm type IV secretion system. Mol. Microbiol. 62: 1278-91.

    2. Vincent CD, Buscher BA, Friedman JR. Williams LA, Bardill P, Vogel JP. 2006. Identification of non-dot/icm suppressors of the Legionella pneumophila dotL lethality phenotype. J. Bacteriol. 188:8231.

    3. Vincent CA and Vogel JP. 2006. The Legionella pneumophila IcmS-LvgA protein complex is important for Dot/Icm-dependent intracellular growth. Mol. Microbiol. 61:596-613.

    4. Sexton JA, Yeo H-J, Vogel JP. 2005. The Legionella pneumophila type IV secretion ATPase DotB functions in substrate selection. Mol. Microbiol. 57:70-84.

    5. Bardill JP, Miller JL, Vogel JP. 2005. IcmS-dependent translocation of SdeA into macrophages by the Legionella pneumophila type IV secretion system. Mol. Microbiol. 56:90-103.

    6. Buscher BA, Conover GM, Miller JL, Meyers SN, Isberg RR, Vogel JP. 2005. The DotL protein, a member of the TraG-coupling protein family, is essential for viability of the Legionella pneumophila strain Lp02. J. Bacteriol. 187:2927-38.

    7. Sexton JA, Miller JL, Yoneda A, Kehl-Fie TE, Vogel JP. 2004. Legionella pneumophila DotU and IcmF are required for stability of the Dot/Icm complex. Infect. Immun. 72:5983-92.

    8. Sexton JA & Vogel JP. 2004. Regulation of hypercompetence in Legionella pneumophila. J. Bacteriol. 186:3814-25.

    9. Sexton JA, Pinkner JS, Roth R, Heuser JE, Hultgren SJ, and Vogel JP. 2004. The Legionella pneumophila PilT homologue DotB exhibits ATPase activity that is critical for intracellular growth. J. Bacteriol. 186:1658-66.

    10. Conover GM, Derre I, Vogel JP, Isberg RR. 2003. The Legionella pneumophila LidA protein: a translocated substrate of the Dot/Icm system associated with maintenance of bacterial integrity. Mol Microbiol. 48:305-21.

    11. Vogel JP, Andrews HL, Wong SK, Isberg RR. 1998. Conjugative transfer by the virulence system of Legionella pneumophila. Science. 279:873-876.

    12. Kirby JE, Vogel JP, Andrews HL, Isberg RR. 1998. Evidence for pore forming ability by Legionella pneumophila. Mol. Microbiol. 27:323-336.

    13. Andrews HL, Vogel JP, Isberg RR. 1998. Identification of linked Legionella pneumophila genes essential for intracellular growth and evasion of the endocytic pathway. Infect. Immun. 66:950-958.

    14. McClellan AJ, Endres JB, Vogel JP, Palazzi D, Rose MD, Brodsky JL. 1998. Specific molecular chaperone interactions and an ATP-dependent conformational change are required during post-translational protein translocation into the yeast ER. Mol. Biol. Cell. 9:3533-45

    15. Vogel JP, Roy C, Isberg RR. 1996. Use of salt to isolate Legionella pneumophila mutants unable to replicate in macrophages. Ann. N.Y. Acad. Sciences. 797:271.

    16. Flach JM, Bossie M, Vogel JP, Corbett A, Jinks T, Willins DA Silver PA. 1995. A yeast RNA-binding protein shuttles between the nucleus and the cytoplasm. Mol. Cell Biol. 14:8399-8407.

    17. Vogel JP, Lee JN, Kirsch D, Rose MD and Sztul E. 1993. Brefeldin A causes a defect in secretion in Saccharomyces cerevisiae. J. Biol. Chem. 268:3040-3043.

    18. Sanders SL, Whitfield KM, Vogel JP, Rose MD, Schekman RS. 1992. Sec61p and BiP directly facilitate polypeptide translocation into the ER. Cell. 69:353-366.

    19. Vogel JP, Misra LM, Rose MD. 1990. Loss of BiP/GRP78 function blocks translocation of secretory proteins in yeast. J. Cell Biol. 110:1885-1895.

    20. Rose MD, Misra LM, and Vogel JP. 1989. KAR2, a karyogamy gene is the yeast homolog of the mammalian Bip/GRP78 gene. Cell. 57:1211-1221.

    21. Clarke S, Vogel JP, Deschenes RJ, Stock J. 1988. Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxy methyltransferases. Proc. Natl. Acad. Sci. USA. 85:4643-4647.