Primary Faculty

Research Interest:
We study infection and evolutionary mechanisms in Helicobacter pylori, a widespread, genetically diverse bacterial pathogen implicated in peptic ulcer disease and gastric cancer.

Research Interest:
Molecular genetics and genomics of the protozoan parasite Leishmania major, including virulence in the insect and mammalian hosts, and strategies for control.

Research Interest:
Pathogenesis of infections caused by Gram positive bacteria. Gene regulation and mechanisms of toxin secretion by Group A streptococci.

Research Interest:
The pathogenic yeast Cryptococcus neoformans, using biochemistry, cell and molecular biology, genetics, and genomic approaches to elucidate its fascinating biology and pathogenesis.

Research Interest:
RNA virus evolution. Molecular biology of alphaviruses. Alphavirus gene expression vectors. Antiviral drug design.

Research Interest:
Our lab blends genetic, genomic, imaging, structural, biochemical, clinical and translational strategies to study the interface between a pathogen and itís host.

Research Interest:
The Lewis lab integrates bacterial genetics, analytical glycobiology, comparative phylogeny and infection models to study the evolution and functions of complex carbohydrates during infection. Mechanistic and clinical studies focus on pathogens of the female reproductive tract.

Research Interest:
Signal transduction, cell wall biosynthesis and resistance to oxidative and nitrosative stresses  in the pathogenic fungus, Cryptococcus neoformans.

Research Interest:
We are using comparative genomics and genetics to define virulence determinants in the model intracellular parasite Toxoplasma gondii. and to examine the cellular and molecular basis of motility and host cell invasion.

Research Interest:
Molecular pathogenesis of Mycobacterium tuberculosis.

Research Interest:
Structural, functional and mechanistic studies of erythrocyte invasion by Plasmodium parasites.

Vogel, Joseph
Associate Professor of Molecular Microbiology

Research Interest:
We study the ability of Legionella pneumophila and Coxiella burnetii to replicate inside host cells, specifically focusing on the pathogensí type IV secretion systems.

Wang, David
Associate Professor of Molecular Microbiology

Research Interest:
Detection, identification and characterization of novel and emerging viruses.

Yu, Dong
Assistant Professor of Molecular Microbiology

Research Interest:
We study host and viral processes fundamental to the biology of cytomegalovirus, and delineate molecular mechanisms of cytomegalovirus replication and pathogenesis.