Professor of Molecular Microbiology

Wang Lab website

Research Interests:

Detection, identification and characterization of novel and emerging viruses.

Division of Biology and Biomedical Sciences profile

Office Address:

Departments of Molecular Microbiology and Pathology & Immunology
Washington University School of Medicine
8250 McDonnell Pediatric Research Building
MSC 8230-16-08250
660 S. Euclid Ave.
St. Louis, MO 63110

Phone, office: 314-286-1123
Phone, lab: 314-286-1124
Fax: 314-362-1232
Email: davewang [at] wusm.wustl.edu

Education:
1998-2004 Postdoctoral Fellow, University of California, San Francisco
1992-1998 Ph.D. Biological Chemistry, Massachusetts Institute of Technology
1988-1992 B.S. Chemistry, Stanford University

Academic Positions:
2018-present   Professor of Molecular Microbiology and of Pathology and Immunology2004-2010-2018    Associate Professor of Molecular Microbiology and of Pathology and Immunology
2010    Assistant Professor of Molecular Microbiology and of Pathology and Immunology

Selected Publications:
Smith B, Janowski A,  Danis J, Harvey I, Zhao H, Dai Y, Farnsworth C, Gronowski A, Roper S, Fremont D, and Wang D. “Seroprevalence of SARS-CoV-2 antibodies in children and adults in St. Louis, Missouri” mSphere 2021 2021 Feb 3;6(1):e01207-20.

Jiang H, Sandoval Del Prado LE, Leung C, Wang D. “Huntingtin-interacting protein family members have a conserved pro-viral function from Caenorhabditis elegans to humans” PNAS. 2020 Sep 8;117(36):22462-22472.

Jiang H, Leung C, Tahan S, Wang D “Entry by multiple picornaviruses is dependent on a pathway that includes TNK2, WASL, and NCK1.” Elife. 2019 Nov 26;8. pii: e50276

Richaud A, Frézal L, Tahan S, Zhao G, Kaur T, Wang D*, Felix MA “Vertical transmission in Caenorhabditis nematodes of RNA molecules encoding a viral RNA-dependent RNA polymerase” PNAS 2019 Nov 18. pii: 201903903.

Janowski AB, Klein RS, Wang D “Differential in vitro infection of neural cells by astroviruses” mBio 2019 Jul 9;10(4).  PMCID: PMC6747723.

Zhao G, Droit L, Gilbert MH, Schiro FR, Dider PJ, Si X, Paredes A, Handley SA, Virgin HW, Bohm RP, Wang D “Virome biogeography in the lower gastrointestinal tract of rhesus macaques with chronic diarrhea” Virology 2019 Jan 15;527:77-88.

Le Pen J, Jiang H, Di Domenico T, Kneuss E, Kosalka J, Leung C, Morgan M, Much C, Rudolph KLM, Enright AJ, O’Carroll D, Wang D, Miska EA “Terminal urdiylyltransferases target RNA viruses as part of the innate immune system” Nature Structural and Molecular Biology 2018 10.1038/s41594-018-0106-9. PMCID: PMC6130846.

Krishnamurthy S and Wang D “Extensive conservation of prokaryotic ribosome binding site sequences in known and novel picobirnaviruses” Virology 2018 Jan 12;516:108-114.

Blatter J, Sweet SC, Conrad C, Danziger-Isakov LA, Faro A, Goldfarb SB, Hayes D, Melicoff E, Schecter M, Storch G, Visner GA, Williams NM, Wang D  “Anellovirus loads are associated with short- and long-term outcomes in pediatric lung transplantation” Pediatric Transplantation 2018 Feb;22(1). PMCID: PMC5811341.

Jiang H, Chen K, Sandoval L, Leung C, Wang D “An evolutionarily conserved pathway required for Orsay virus infection of C. elegans” mBio 2017: 8(5). pii: e00940-17.

Janowski AB, Bauer I, Holtz L, Wang D “Propagation of astrovirus VA1, a neurotropic human astrovirus, in cell culture”. J. Virol. 2017: pii: JVI.00740-17. Krishnamurthy S, Janowski AB, Zhao G, Barouch D, Wang D “Hyperexpansion of RNA bacteriophage diversity” PLoS Biology 2016: 14(3): e1002409. PMCID: PMC4807089.