Recent publications
Development and Immunogenicity of a Prototype Multivalent Group B Streptococcus Bioconjugate Vaccine
Jeremy A Duke , Amy V Paschall , Lloyd S Robinson , Cory J Knoot , Evgeny Vinogradov , Nichollas E Scott , Mario F Feldman , Fikri Y Avci , Christian M Harding
PMID: 34633812 DOI: 10.1021/acsinfecdis.1c00415
ACS Infect. Dis 12 November 2021
Commensal Cryptosporidium colonization elicits a cDC1-dependent Th1 response that promotes intestinal homeostasis and limits other infections
Emilie V Russler-Germain , Jisun Jung , Aidan T Miller , Shannon Young , Jaeu Yi , Alec Wehmeier , Lindsey E Fox , Kristen J Monte , Jiani N Chai , Devesha H Kulkarni , Lisa J Funkhouser-Jones , Georgia Wilke , Vivek Durai , Bernd H Zinselmeyer , Rafael S Czepielewski , Suellen Greco , Kenneth M Murphy , Rodney D Newberry , L David Sibley , Chyi-Song Hsieh
PMID: 34715017 DOI: 10.1016/j.immuni.2021.10.002
Immunity 9 November 2021
A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants
Novalia Pishesha , Thibault J Harmand , Paul W Rothlauf , Patrique Praest , Ryan K Alexander , Renate van den Doel , Mariel J Liebeskind , Maria A Vakaki , Nicholas McCaul , Charlotte Wijne , Elisha Verhaar , William Pinney 3rd , Hailey Heston , Louis-Marie Bloyet , Marjorie Cornejo Pontelli , Ma Xenia G Ilagan , Robert Jan Lebbink , William J Buchser , Emmanuel J H J Wiertz , Sean P J Whelan , Hidde L Ploegh
PMID: 34654739 DOI: 10.1073/pnas.2116147118
PNAS 2 November 2021
High Seropositivity Rate of Neutralizing Antibodies to Astrovirus VA1 in Human Populations
Andrew B Janowski , Macee C Owen , Holly Dudley , Tomás López , Rafaela Espinosa , Memory Elvin-Lewis , Alejandro Colichon , Carlos F Arias , Peter D Burbelo , David Wang
PMID: 34468168 DOI: 10.1128/mSphere.00484-21
ASM Journals mSphere 27 October 2021
Isolation of Reconstructed Functional Ribonucleoprotein Complexes of Machupo Virus
Jesse D Pyle , Sean P J Whelan
PMID: 34432522 DOI: 10.1128/JVI.01054-21
Journal of Virology 27 October 2021
Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD
John M Errico , Haiyan Zhao , Rita E Chen , Zhuoming Liu , James Brett Case , Meisheng Ma , Aaron J Schmitz , Michael J Rau , James A J Fitzpatrick , Pei-Yong Shi , Michael S Diamond , Sean P J Whelan , Ali H Ellebedy , Daved H Fremont
PMID: 34655519 DOI: 10.1016/j.celrep.2021.109881
A Cell Press journal 26 October 2021
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells
Matthew Mahoney , Vishnu C Damalanka , Michael A Tartell , Dong Hee Chung , André Luiz Lourenço , Dustin Pwee , Anne E Mayer Bridwell , Markus Hoffmann , Jorine Voss , Partha Karmakar , Nurit P Azouz , Andrea M Klingler , Paul W Rothlauf , Cassandra E Thompson , Melody Lee , Lidija Klampfer , Christina L Stallings , Marc E Rothenberg , Stefan Pöhlmann , Sean P J Whelan , Anthony J O’Donoghue , Charles S Craik , James W Janetka
PMID: 34635581 DOI: 10.1073/pnas.2108728118
PNAS 26 October 2021
Neutralizing Monoclonal Antibodies That Target the Spike Receptor Binding Domain Confer Fc Receptor-Independent Protection against SARS-CoV-2 Infection in Syrian Hamsters
Wen Su , Sin Fun Sia , Aaron J Schmitz , Traci L Bricker , Tyler N Starr , Allison J Greaney , Jackson S Turner , Bassem M Mohammed , Zhuoming Liu , Ka Tim Choy , Tamarand L Darling , Astha Joshi , Ka Man Cheng , Alvina Y L Wong , Houda H Harastani , John M Nicholls , Sean P J Whelan , Jesse D Bloom , Hui-Ling Yen , Ali H Ellebedy , Adrianus C M Boon
PMID: 34517754PMCID: DOI: 10.1128/mBio.02395-21
ASM Journals mBio 26 October 2021
S100A8/A9 in COVID-19 pathogenesis: Impact on clinical outcomes
Leah Mellett , Shabaana A Khader
PMID: 34728150 PMCID: PMC8520505 DOI: 10.1016/j.cytogfr.2021.10.004
Cytokine & Growth Factor Reviews 17 October 2021
Cryptococcus neoformans Cda1 and Cda2 coordinate deacetylation of chitin during infection to control fungal virulence
Rajendra Upadhya , Woei C Lam , Camaron R Hole , Danealle Parchment , Chrono K Lee , Charles A Specht , Stuart M Levitz , Jennifer K Lodge
PMID: 34712865 PMCID: PMC8529172 DOI: 10.1016/j.tcsw.2021.100066
The Cell Surface 15 October 2021