Recent publications

Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2. Case JB, Rothlauf PW, Chen RE, Liu Z, Zhao H, Kim AS, Bloyet LM, Zeng Q, Tahan S, Droit L, Ilagan MXG, Tartell MA, Amarasinghe G, Henderson JP, Miersch S, Ustav M, Sidhu S, Virgin HW, Wang D, Ding S, Corti D, Theel ES, Fremont DH, Diamond MS, Whelan SPJ. Cell Host Microbe. 2020 Jul 3:S1931-3128(20)30362-0. doi: 10.1016/j.chom.2020.06.021.  PMID: 32735849

Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus. Korber B, Fischer WM, Gnanakaran S, Yoon H, Theiler J, Abfalterer W, Hengartner N, Giorgi EE, Bhattacharya T, Foley B, Hastie KM, Parker MD, Partridge DG, Evans CM, Freeman TM, de Silva TI; Sheffield COVID-19 Genomics Group, McDanal C, Perez LG, Tang H, Moon-Walker A, Whelan SP, LaBranche CC, Saphire EO, Montefiori DC. Cell. 2020 Jul 3:S0092-8674(20)30820-5. doi: 10.1016/j.cell.2020.06.043.  PMID: 32697968

Formation of Lung Inducible Bronchus Associated Lymphoid Tissue Is Regulated by Mycobacterium tuberculosis Expressed Determinants. Tussiwand R, Behnke MS, Kretzer NM, Grajales-Reyes GE, Murphy TL, Schreiber RD, Murphy KM, Sibley LD. mSphere. 2020 Jul 15;5(4):e00634-20. doi: 10.1128/mSphere.00634-20.  PMID: 32669460

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein. Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, MacRenaris KW, Jones T, Day S, Myers L, Eun-Hyung Lee F, Nguyen DC, Sanz I, Martinez DR, Rothlauf PW, Bloyet LM, Whelan SPJ, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr. Nat Med. 2020 Jul 10. doi: 10.1038/s41591-020-0998-x.  PMID: 32651581

Structural basis for effector protein recognition by the Dot/Icm Type IVB coupling protein complex. Kim H, Kubori T, Yamazaki K, Kwak MJ, Park SY, Nagai H, Vogel JP, Oh BH. Nat Commun. 2020 May 26;11(1):2623. doi: 10.1038/s41467-020-16397-0. PMID: 32457311 [PubMed – in process]

An atypical lipoteichoic acid from <i>Clostridium perfringens</i> elicits a broadly cross-reactive and protective immune response. Wenzel CQ, Mills DC, Dobruchowska JM, Vlach J, Nothaft H, Nation P, Azadi P, Melville SB, Carlson RW, Feldman MF, Szymanski CM. J Biol Chem. 2020 May 18. pii: jbc.RA119.009978. doi: 10.1074/jbc.RA119.009978. [Epub ahead of print] PMID: 32424044 [PubMed – as supplied by publisher]

Cryptococcus neoformans evades pulmonary immunity by modulating xylose precursor transport. Li LX, Hole CR, Rangel-Moreno J, Khader SA, Doering TL. Infect Immun. 2020 May 18. pii: IAI.00288-20. doi: 10.1128/IAI.00288-20. [Epub ahead of print] PMID: 32423915 [PubMed – as supplied by publisher]

Optimizing Pyrazolopyrimidine Inhibitors of Calcium Dependent Protein Kinase 1 for Treatment of Acute and Chronic Toxoplasmosis. Janetka JW, Hopper AT, Yang Z, Barks J, Dhason MS, Wang Q, Sibley LD. J Med Chem. 2020 Jun 1. doi: 10.1021/acs.jmedchem.0c00419. [Epub ahead of print] PMID: 32420739 [PubMed – as supplied by publisher]

TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes. Zang R, Gomez Castro MF, McCune BT, Zeng Q, Rothlauf PW, Sonnek NM, Liu Z, Brulois KF, Wang X, Greenberg HB, Diamond MS, Ciorba MA, Whelan SPJ, Ding S. Sci Immunol. 2020 May 13;5(47). pii: eabc3582. doi: 10.1126/sciimmunol.abc3582. PMID: 32404436 [PubMed – indexed for MEDLINE]